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10‑vial kitCognitiveRetaNord Semax research peptide — 10-vial kit
ACTH(4-10) analogue Nootropic peptide

Semax

ACTH(4–10)-derived research peptide · 10-vial kit

Synthetic ACTH-fragment peptide

Semax is a synthetic peptide derived from a fragment of ACTH (4–10). Developed in Russia, it is studied in neuropeptide and cognitive-research contexts.

€35910 mg · 10-vial kitIn stock
Vial size
Kit size

Both kit sizes ship within the EU — free shipping either way.

Plain, unbranded packaging. No product names, no logos — nothing on the outside indicating what is inside. Tracked to a DPD Locker or your address.

Guaranteed delivery. If your order doesn't reach you, we ship it again free — lost, damaged or stolen.

Purity 99%+ HPLC
Kit 10 or 30 vials
Ships in 24–48h

For laboratory and in vitro research use only. Not for human or veterinary use, and not for use in diagnostic procedures.

EU-stocked & shippedDispatched in 24–48hFree shipping10 or 30-vial kitsSealed, lyophilized vials

About Semax

Semax is a synthetic heptapeptide based on the 4–10 fragment of adrenocorticotropic hormone (ACTH), modified for stability. Developed in Russia, it is studied as a neuropeptide research tool in cognition and neuroprotection contexts. Supplied as a lyophilized 10-vial kit.

RetaNord supplies Semax as fixed kits of 10 or 30 lyophilized vials, each verified at 99%+ identity purity by independent third-party HPLC (Janoshik), and every kit ships with a lot-specific Certificate of Analysis. Supplied for laboratory and in vitro research use only.

How Semax works

Semax is a synthetic heptapeptide: the ACTH(4–10) fragment extended at the C-terminus with Pro-Gly-Pro. That tripeptide tail is the whole point — it slows enzymatic breakdown, so the molecule survives long enough to be studied.

It is built from the fragment of ACTH that lacks the region required for corticotropic activity, so the literature treats it as a neuropeptide rather than a hormone analogue. Reported effects centre on BDNF and neurotrophin expression.

Mechanistic summary drawn from published literature, provided for research context only. Not a therapeutic claim.

What the research shows

A 2016 paper in Journal of Inorganic Biochemistry examines how N-terminal acetylation changes the molecule; a 2020 study applies a functional-connectomic approach to Semax and Selank together.

Semax was developed in Russia and most of its literature is Russian-language or Russian-authored. It is not approved in the EU or the US.

An educational summary of published literature. It is not a claim about any outcome for any buyer, and RetaNord supplies this compound for laboratory research use only.

Storage & handling

Sealed, lyophilized vials. 2–8 °C for routine storage; −20 °C or below for long-term. Room temperature is for transit and handling only — it is not a storage state for a peptide.

Once reconstituted. Keep at 2–8 °C and never freeze — ice crystals cause irreversible damage. Reconstituted with bacteriostatic water (0.9% benzyl alcohol) a vial is commonly used within about 30 days; with plain sterile water, within 24–48 hours.

Keep vials sealed and protected from light, and minimise freeze–thaw cycles of frozen stock — each cycle costs potency.

Work out concentration and draw volume in the reconstitution calculator →

Specifications

CategoryCognitive & Mood
Compound classSynthetic ACTH(4–10)-derived peptide
Presentation10 vials per kit · lyophilized
Available sizes10 mg per vial
CAS number80714-61-0
Molecular formulaC37H51N9O10S
Molecular weight≈ 814 g/mol
Physical formSterile-filtered, freeze-dried
Identity purity99%+ (HPLC)
Independent testingJanoshik · third-party HPLC
Storage2–8°C; −20°C long term
DocumentationLot-specific Certificate of Analysis
Semax Certificate of AnalysisCertificate of Analysis — batch VJ541539Independent third-party testing by Janoshik · HPLC purity 99.357% and content verified.View the full report →

References & research

Selected peer-reviewed literature via PubMed, provided for educational context. A reference does not imply a clinical claim for RetaNord products.

  1. Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties.
  2. Functional Connectomic Approach to Studying Selank and Semax Effects.

Semax — questions

Do the kits come with a Certificate of Analysis?

Yes — every kit ships with a lot-specific third-party Certificate of Analysis: independent HPLC purity and content testing by Janoshik, with the batch matching your vials. View the current CoA.

What class of peptide is Semax?

A synthetic neuropeptide derived from an ACTH(4–10) fragment. RetaNord supplies it strictly for laboratory research use.

Why is this sold as a 10-vial kit?

These research compounds are supplied in fixed kits of 10 identical vials — the standard research quantity. One kit (10 vials) is the minimum order to the EU.

How should Semax be stored?

Sealed lyophilized vials keep at 2–8 °C, or −20 °C for long-term storage. Once reconstituted, keep refrigerated and never freeze it. See storage & handling for the full detail.

How do I work out the concentration?

The volume of bacteriostatic water you add sets the concentration — the vial size alone does not. Enter your vial size and diluent volume in the reconstitution calculator to calculate the concentration for your assay.

How is Semax related to Selank?

Both are Russian-developed synthetic heptapeptides built the same way — a short natural sequence extended with a Pro-Gly-Pro tail for stability. Semax comes from ACTH(4–10); Selank comes from tuftsin.

Documented peptides, shipped from the EU.

Every RetaNord kit ships within 24–48 hours, discreetly packaged and tracked. All kits ship within the EU. For laboratory research use only.

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