RetaNord sells research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Please confirm before continuing.
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Synthetic ACTH-fragment peptide
Semax is a synthetic peptide derived from a fragment of ACTH (4–10). Developed in Russia, it is studied in neuropeptide and cognitive-research contexts.
Both kit sizes ship within the EU — free shipping either way.
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For laboratory and in vitro research use only. Not for human or veterinary use, and not for use in diagnostic procedures.
Semax is a synthetic heptapeptide based on the 4–10 fragment of adrenocorticotropic hormone (ACTH), modified for stability. Developed in Russia, it is studied as a neuropeptide research tool in cognition and neuroprotection contexts. Supplied as a lyophilized 10-vial kit.
RetaNord supplies Semax as fixed kits of 10 or 30 lyophilized vials, each verified at 99%+ identity purity by independent third-party HPLC (Janoshik), and every kit ships with a lot-specific Certificate of Analysis. Supplied for laboratory and in vitro research use only.
Semax is a synthetic heptapeptide: the ACTH(4–10) fragment extended at the C-terminus with Pro-Gly-Pro. That tripeptide tail is the whole point — it slows enzymatic breakdown, so the molecule survives long enough to be studied.
It is built from the fragment of ACTH that lacks the region required for corticotropic activity, so the literature treats it as a neuropeptide rather than a hormone analogue. Reported effects centre on BDNF and neurotrophin expression.
Mechanistic summary drawn from published literature, provided for research context only. Not a therapeutic claim.
A 2016 paper in Journal of Inorganic Biochemistry examines how N-terminal acetylation changes the molecule; a 2020 study applies a functional-connectomic approach to Semax and Selank together.
Semax was developed in Russia and most of its literature is Russian-language or Russian-authored. It is not approved in the EU or the US.
An educational summary of published literature. It is not a claim about any outcome for any buyer, and RetaNord supplies this compound for laboratory research use only.
Sealed, lyophilized vials. 2–8 °C for routine storage; −20 °C or below for long-term. Room temperature is for transit and handling only — it is not a storage state for a peptide.
Once reconstituted. Keep at 2–8 °C and never freeze — ice crystals cause irreversible damage. Reconstituted with bacteriostatic water (0.9% benzyl alcohol) a vial is commonly used within about 30 days; with plain sterile water, within 24–48 hours.
Keep vials sealed and protected from light, and minimise freeze–thaw cycles of frozen stock — each cycle costs potency.
Work out concentration and draw volume in the reconstitution calculator →
| Category | Cognitive & Mood |
|---|---|
| Compound class | Synthetic ACTH(4–10)-derived peptide |
| Presentation | 10 vials per kit · lyophilized |
| Available sizes | 10 mg per vial |
| CAS number | 80714-61-0 |
| Molecular formula | C37H51N9O10S |
| Molecular weight | ≈ 814 g/mol |
| Physical form | Sterile-filtered, freeze-dried |
| Identity purity | 99%+ (HPLC) |
| Independent testing | Janoshik · third-party HPLC |
| Storage | 2–8°C; −20°C long term |
| Documentation | Lot-specific Certificate of Analysis |
Certificate of Analysis — batch VJ541539Independent third-party testing by Janoshik · HPLC purity 99.357% and content verified.View the full report →Selected peer-reviewed literature via PubMed, provided for educational context. A reference does not imply a clinical claim for RetaNord products.
Yes — every kit ships with a lot-specific third-party Certificate of Analysis: independent HPLC purity and content testing by Janoshik, with the batch matching your vials. View the current CoA.
A synthetic neuropeptide derived from an ACTH(4–10) fragment. RetaNord supplies it strictly for laboratory research use.
These research compounds are supplied in fixed kits of 10 identical vials — the standard research quantity. One kit (10 vials) is the minimum order to the EU.
Sealed lyophilized vials keep at 2–8 °C, or −20 °C for long-term storage. Once reconstituted, keep refrigerated and never freeze it. See storage & handling for the full detail.
The volume of bacteriostatic water you add sets the concentration — the vial size alone does not. Enter your vial size and diluent volume in the reconstitution calculator to calculate the concentration for your assay.
Both are Russian-developed synthetic heptapeptides built the same way — a short natural sequence extended with a Pro-Gly-Pro tail for stability. Semax comes from ACTH(4–10); Selank comes from tuftsin.
Every RetaNord kit ships within 24–48 hours, discreetly packaged and tracked. All kits ship within the EU. For laboratory research use only.
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