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10‑vial kitIncretinRetaNord Semaglutide research peptide — 10-vial kit
GLP-1 agonist Metabolic · GLP-1

Semaglutide

GLP-1 receptor agonist · 10-vial research kit

Modified GLP-1 analogue

Semaglutide is a synthetic GLP-1 receptor agonist — a modified analogue of human GLP-1 with a fatty-acid chain that greatly extends its half-life. It is the single-receptor benchmark against which newer dual- and triple-agonist peptides are compared.

€5595 mg · 10-vial kitIn stock
Vial size
Kit size

Both kit sizes ship within the EU — free shipping either way.

Plain, unbranded packaging. No product names, no logos — nothing on the outside indicating what is inside. Tracked to a DPD Locker or your address.

Guaranteed delivery. If your order doesn't reach you, we ship it again free — lost, damaged or stolen.

Purity 99%+ HPLC
Kit 10 or 30 vials
Ships in 24–48h

For laboratory and in vitro research use only. Not for human or veterinary use, and not for use in diagnostic procedures.

EU-stocked & shippedDispatched in 24–48hFree shipping10 or 30-vial kitsSealed, lyophilized vials

About Semaglutide

Semaglutide is a synthetic analogue of the human incretin hormone GLP-1, structurally modified with a C18 fatty-diacid chain that extends its plasma half-life to around a week. It is one of the most-studied peptides in the incretin class and the reference point for single-receptor agonism in metabolic research.

RetaNord supplies Semaglutide as fixed kits of 10 or 30 lyophilized vials, each verified at 99%+ identity purity by independent third-party HPLC (Janoshik), and every kit ships with a lot-specific Certificate of Analysis. Supplied for laboratory and in vitro research use only.

How Semaglutide works

Semaglutide is a GLP-1 receptor agonist — an analogue of the human incretin hormone GLP-1, sharing most of its sequence. Two amino-acid substitutions make it resistant to enzymatic degradation, and a C18 fatty-diacid chain attached through a short linker promotes binding to serum albumin.

That albumin binding is what stretches the plasma half-life to roughly a week, which is why published work uses a once-weekly rather than a daily schedule. It engages a single incretin receptor — the reference point against which the dual- and triple-agonist molecules that followed are measured.

Mechanistic summary drawn from published literature, provided for research context only. Not a therapeutic claim.

What the research shows

Semaglutide was evaluated in the STEP programme of randomised trials in overweight and obesity, and in the SUSTAIN programme in type 2 diabetes. A 2025 randomised trial compared it head-to-head with tirzepatide.

Where it sits in the class: semaglutide targets GLP-1 alone, tirzepatide adds GIP, and retatrutide adds glucagon as a third receptor. Full breakdown in the comparison, with primary sources in the references below.

An educational summary of published literature. It is not a claim about any outcome for any buyer, and RetaNord supplies this compound for laboratory research use only.

Storage & handling

Sealed, lyophilized vials. 2–8 °C for routine storage; −20 °C or below for long-term. Room temperature is for transit and handling only — it is not a storage state for a peptide.

Once reconstituted. Keep at 2–8 °C and never freeze — ice crystals cause irreversible damage. Reconstituted with bacteriostatic water (0.9% benzyl alcohol) a vial is commonly used within about 30 days; with plain sterile water, within 24–48 hours.

Keep vials sealed and protected from light, and minimise freeze–thaw cycles of frozen stock — each cycle costs potency.

Work out concentration and draw volume in the reconstitution calculator →

Specifications

CategoryIncretin receptor agonist
Compound classSynthetic peptide — GLP-1 receptor agonist
Presentation10 vials per kit · lyophilized
Available sizes5 · 10 · 15 · 20 mg per vial
CAS number910463-68-2
Molecular formulaC187H291N45O59
Molecular weight≈ 4114 g/mol
Physical formSterile-filtered, freeze-dried
Identity purity99%+ (HPLC)
Independent testingJanoshik · third-party HPLC
Storage2–8°C; −20°C long term
DocumentationLot-specific Certificate of Analysis
Semaglutide Certificate of AnalysisCertificate of Analysis — batch VX551552Independent third-party testing by Janoshik · HPLC purity 99.452% and content verified.View the full report →

References & research

Selected peer-reviewed literature via PubMed, provided for educational context. A reference does not imply a clinical claim for RetaNord products.

  1. Once-Weekly Semaglutide in Adults with Overweight or Obesity.
  2. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.

Semaglutide — questions

Do the kits come with a Certificate of Analysis?

Yes — every kit ships with a lot-specific third-party Certificate of Analysis: independent HPLC purity and content testing by Janoshik, with the batch matching your vials. View the current CoA.

How does it differ from tirzepatide and retatrutide?

Semaglutide targets one receptor (GLP-1); tirzepatide targets two (GIP + GLP-1); retatrutide targets three (GLP-1 + GIP + glucagon). All are studied in the same incretin research family.

Why is this sold as a 10-vial kit?

These research compounds are supplied in fixed kits of 10 identical vials — the standard research quantity. One kit (10 vials) is the minimum order to the EU.

How should Semaglutide be stored?

Sealed lyophilized vials keep at 2–8 °C, or −20 °C for long-term storage. Once reconstituted, keep refrigerated and never freeze it. See storage & handling for the full detail.

How do I work out the concentration?

The volume of bacteriostatic water you add sets the concentration — the vial size alone does not. Enter your vial size and diluent volume in the reconstitution calculator to calculate the concentration for your assay.

Is this the same as the branded products?

Semaglutide is the molecule; Ozempic, Wegovy and Rybelsus are brand names of approved medicines that contain it. RetaNord supplies the research compound — not those products, and not for human use.

Documented peptides, shipped from the EU.

Every RetaNord kit ships within 24–48 hours, discreetly packaged and tracked. All kits ship within the EU. For laboratory research use only.

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